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Mutations Affecting the Ability of the Escherichia coli UmuD′ Protein To Participate in SOS Mutagenesis

The products of the SOS-regulated umuDC operon are required for most UV and chemical mutagenesis in Escherichia coli, a process that results from a translesion synthesis mechanism. The UmuD protein is activated for its role in mutagenesis by a RecA-facilitated autodigestion that removes the N-termin...

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Main Authors: Ohta, Toshihiro, Sutton, Mark D., Guzzo, Angelina, Cole, Shannon, Ferentz, Ann E., Walker, Graham C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC103547/
https://ncbi.nlm.nih.gov/pubmed/9864328
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