Branch migration inhibition in PCR-amplified DNA: homogeneous mutation detection

A novel method for detection of any mutation located within a PCR-amplified DNA sequence was demonstrated. The method is based on the inhibition of spontaneous DNA branch migration. Partial duplexes produced by PCR amplification of a test and a reference genomic DNA sample anneal to form four-strand...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Lishanski, Alla, Kurn, Nurith, Ullman, Edwin F.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2000
Fag:	NAR Methods Online
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103315/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756209/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.9.e42
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