Accurate and rapid modeling of iron–bleomycin-induced DNA damage using tethered duplex oligonucleotides and electrospray ionization ion trap mass spectrometric analysis

Bleomycin B(2) (BLM) in the presence of iron [Fe(II)] and O(2) catalyzes single-stranded (ss) and double-stranded (ds) cleavage of DNA. Electrospray ionization ion trap mass spectrometry was used to monitor these cleavage processes. Two duplex oligonucleotides containing an ethylene oxide tether bet...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Harsch, Andreas, Marzilli, Lisa A., Bunt, Richard C., Stubbe, Joanne, Vouros, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2000
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC103282/
https://ncbi.nlm.nih.gov/pubmed/10756200
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