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Controlled acute trial of a thyrotrophin releasing hormone analogue (RX77368) in motor neuron disease.

Twenty five patients with motor neuron disease completed a double blind randomised cross over trial of RX77368, a stabilised TRH analogue, iv over 2 hours against saline. Temporary improvement in bulbar symptoms including speech, respiratory parameters, tongue movements and swallowing were seen. Fas...

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Autors principals: Guiloff, R J, Eckland, D J, Demaine, C, Hoare, R C, MacRae, K D, Lightman, S L
Format: Artigo
Idioma:Inglês
Publicat: 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1032465/
https://ncbi.nlm.nih.gov/pubmed/3119776
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