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Levodopa peripheral pharmacokinetics and duration of motor response in Parkinson's disease.

To assess the relative influence of central pharmacodynamic and peripheral pharmacokinetic factors on the duration of motor response to levodopa, the relationship between motor function and plasma levodopa levels was studied in 31 Parkinsonian patients. Duration of benefit from single levodopa doses...

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Autors principals: Kempster, P A, Frankel, J P, Bovingdon, M, Webster, R, Lees, A J, Stern, G M
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1032021/
https://ncbi.nlm.nih.gov/pubmed/2501456
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