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Effect of alpha thalassaemia trait and enhanced gamma chain production on disease severity in beta thalassaemia major and intermedia.

One hundred and twenty patients with homozygous beta thalassaemia were selected to determine the clinical effects of certain genetic factors which may modify disease severity. Genetic analysis defined specific beta thalassaemia mutations, the alpha thalassaemia genotype, and the presence of an XmnI...

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Detalhes bibliográficos
Main Authors: Gringras, P, Wonke, B, Old, J, Fitches, A, Valler, D, Kuan, A M, Hoffbrand, V
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1029678/
https://ncbi.nlm.nih.gov/pubmed/7509151
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