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Mapping of accessible sites for oligonucleotide hybridization on hepatitis delta virus ribozymes

Semi-random libraries of DNA 6mers and RNase H digestion were applied to search for sites accessible to hybridization on the genomic and antigenomic HDV ribozymes and their 3′ truncated derivatives. An approach was proposed to correlate the cleavage sites and most likely sequences of oligomers, memb...

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Bibliografske podrobnosti
Main Authors: Wrzesinski, Jan, Legiewicz, Micha, Ciesiolka, Jerzy
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC102829/
https://ncbi.nlm.nih.gov/pubmed/10734198
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