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Degradation of ribosomal RNA precursors by the exosome

The yeast exosome is a complex of 3′→5′ exonucleases involved in RNA processing and degradation. All 11 known components of the exosome are required during 3′ end processing of the 5.8S rRNA. Here we report that depletion of each of the individual components inhibits the early pre-rRNA cleavages at...

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Pubblicato in:Nucleic Acids Res
Autori principali: Allmang, Christine, Mitchell, Philip, Petfalski, Elisabeth, Tollervey, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102825/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10734186/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.8.1684
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