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NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C

Hu antigen C (HuC) has three RNA-binding domains (RBDs). The N-terminal two, RBD1 and RBD2, are linked in tandem and bind to the AU-rich elements (AREs) in the 3′-untranslated region of particular mRNAs. The solution structures of HuC RBD1 and RBD2 were determined by NMR methods. The HuC RBD1 and RB...

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Udgivet i:Nucleic Acids Res
Principais autores: Inoue, Makoto, Muto, Yutaka, Sakamoto, Hiroshi, Yokoyama, Shigeyuki
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102815/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10734193/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.8.1743
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