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Differential regulation of gene activity and chromatin structure within the human serpin gene cluster at 14q32.1 in macrophage microcell hybrids

The human gene encoding α1-antitrypsin (α1AT, gene symbol PI) is highly expressed in the liver and in cultured hepatoma cells and, to a lesser extent, in macrophages, where transcription originates from a separate upstream promoter. α1AT maps to a region of human chromosome 14q32.1 that includes a r...

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Main Authors: Rollini, Pierre, Fournier, R. E. K.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC102814/
https://ncbi.nlm.nih.gov/pubmed/10734196
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