DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining

Non-homologous DNA end joining (NHEJ) is considered the major pathway of double-strand break (DSB) repair in mammalian cells and depends, among other things, on the DNA end-binding Ku70/80 heterodimer. To investigate the function of Ku in NHEJ we have compared the ability of cell-free extracts from...

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Опубліковано в::	Nucleic Acids Res
Автори:	Feldmann, Elke, Schmiemann, Viola, Goedecke, Wolfgang, Reichenberger, Susanne, Pfeiffer, Petra
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Oxford University Press 2000
Предмети:	Article
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102716/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10871410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.13.2585
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