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The role of 5′-leader length, secondary structure and PABP concentration on cap and poly(A) tail function during translation in Xenopus oocytes

The 5′-cap structure and poly(A) tail of eukaryotic mRNAs function synergistically to promote translation initiation through a physical interaction between the proteins that bind to these regulatory elements. In this study, we have examined the effect of leader length and the presence of secondary s...

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Detalhes bibliográficos
Main Authors: Gallie, Daniel R., Ling, Jun, Niepel, Mario, Morley, Simon J., Pain, Virginia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102682/
https://ncbi.nlm.nih.gov/pubmed/10908358
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