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The nature of the 5′-terminus is a major determinant for DNA processing by Schizosaccharomyces pombe Rad2p, a FEN-1 family nuclease

The nuclease activity of FEN-1 is essential for both DNA replication and repair. Intermediate DNA products formed during these processes possess a variety of structures and termini. We have previously demonstrated that the 5′→3′ exonuclease activity of the Schizosaccharomyces pombe FEN-1 protein Rad...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Alleva, Jeanne L., Doetsch, Paul W.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102672/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10908351/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.15.2893
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