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Precise arrangement of factor-binding sites is required for murine CD4 promoter function

The control of CD4 expression is linked to the signaling events that mediate T-cell development and is directly dependent on the CD4 promoter. The CD4 promoter does not contain functionally redundant sites: all four factor-binding sites must be intact to achieve wild-type activity. Here we demonstra...

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Detalles Bibliográficos
Main Authors: Sarafova, Sophia, Siu, Gerald
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC102665/
https://ncbi.nlm.nih.gov/pubmed/10908321
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