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Accessibility of transcriptionally inactive genes is specifically reduced at homeoprotein-DNA binding sites in Drosophila

We showed previously that homeoproteins bind to multiple DNA sites throughout the length of most genes in Drosophila embryos. Based on a compari­son of in vivo and in vitro DNA binding specificities, we suggested that homeoprotein binding sites on actively transcribed genes are largely accessible, w...

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Detalhes bibliográficos
Main Authors: Carr, Alan, Biggin, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102649/
https://ncbi.nlm.nih.gov/pubmed/10908343
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