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Specific bonding of puromycin to full-length protein at the C-terminus

Puromycin, an analog of the 3′ end of aminoacyl-tRNA, causes premature termination of translation by being linked non-specifically to growing polypeptide chains. Here we report the interesting phenomenon that puromycin acting as a non-inhibitor at very low concentration (e.g. 0.04 µM) can bond only...

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Auteurs principaux: Miyamoto-Sato, Etsuko, Nemoto, Naoto, Kobayashi, Kensei, Yanagawa, Hiroshi
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC102619/
https://ncbi.nlm.nih.gov/pubmed/10666460
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