Transactivation and growth suppression by the gut-enriched Krüppel-like factor (Krüppel-like factor 4) are dependent on acidic amino acid residues and protein–protein interaction

Gut-enriched Krüppel-like factor (GKLF or KLF4) is a pleiotropic (activating and repressive) transcription factor. This study characterizes the mechanisms of transactivation by GKLF. Using a GAL4 fusion assay, the activating domain of murine GKLF was localized to the 109 amino acid residues in the N...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Geiman, Deborah E., Ton-That, Han, Johnson, Jerainne M., Yang, Vincent W.
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 2000
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.5.1106
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