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Mapping Approaches to Gene Identification in Humans

Although a number of human genes that cause disease have been traced through the defective product, most genetic defects are recognized only by phenotype. When the biochemical defect is unknown, a gene can be located only through molecular approaches based on coinheritance (genetic linkage) of the d...

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Detalhes bibliográficos
Main Authors: White, Raymond L., Lalouel, Jean-Marc, Lathrop, G. Mark, Leppert, Mark F., Nakamura, Yusuke, O'Connell, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1025901/
https://ncbi.nlm.nih.gov/pubmed/3479870
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