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Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT)

Telomerase activation is thought to be a critical step in cellular immortalization and carcinogenesis. The human telomerase catalytic subunit (hTERT) is a rate limiting determinant of the enzymatic activity of human telomerase. In the previous study, we identified the proximal 181 bp core promoter r...

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Udgivet i:Nucleic Acids Res
Principais autores: Kyo, Satoru, Takakura, Masahiro, Taira, Takahiro, Kanaya, Taro, Itoh, Hideaki, Yutsudo, Masuo, Ariga, Hiroyoshi, Inoue, Masaki
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102554/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10637317/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.3.669
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