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Activation of c-myc promoter P1 by immunoglobulin κ gene enhancers in Burkitt lymphoma: functional characterization of the intron enhancer motifs κB, E box 1 and E box 2, and of the 3′ enhancer motif PU

Deregulated expression of the proto-oncogene c-myc in Burkitt lymphoma (BL) cells carrying a t(2;8) translocation is mediated by a synergistic interaction of the translocated immunoglobulin (Ig) κ gene intron (κEi) and 3′ (κE3′) enhancers and characterized by a strong activation of the promoter P1....

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Detalhes bibliográficos
Main Authors: Wittekindt, Nicola E., Hörtnagel, Konstanze, Geltinger, Christian, Polack, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102546/
https://ncbi.nlm.nih.gov/pubmed/10637333
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