The specificity of protein–DNA crosslinking by formaldehyde: in vitro and in Drosophila embryos
Formaldehyde crosslinking has been widely used to study binding of specific proteins to DNA elements in intact cells. However, previous studies have not determined if this crosslinker preserves the bona fide pattern of DNA binding. Here we show that formaldehyde crosslinking of Drosophila embryos ma...
Gespeichert in:
| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10606672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.2.e4 |
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