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Disruption of C-Terminal Cytoplasmic Domain of βPS Integrin Subunit Has Dominant Negative Properties in Developing Drosophila

We have analyzed a set of new and existing strong mutations in the myospheroid gene, which encodes the βPS integrin subunit of Drosophila. In addition to missense and other null mutations, three mutants behave as antimorphic alleles, indicative of dominant negative properties. Unlike null alleles, t...

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Pubblicato in:Mol Biol Cell
Autori principali: Jannuzi, Alison L., Bunch, Thomas A., Brabant, Marc C., Miller, Steven W., Mukai, Leona, Zavortink, Michael, Brower, Danny L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Cell Biology 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102274/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11950944/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.01-08-0429
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