Inhibitory Regulation of Rac Activation, Membrane Ruffling, and Cell Migration by the G Protein-Coupled Sphingosine-1-Phosphate Receptor EDG5 but Not EDG1 or EDG3

Sphingosine-1-phosphate (S1P) is a bioactive lysophospholipid that induces a variety of biological responses in diverse cell types. Many, if not all, of these responses are mediated by members of the EDG (endothelial differentiation gene) family G protein-coupled receptors EDG1, EDG3, and EDG5 (AGR1...

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Main Authors: Okamoto, Hiroyuki, Takuwa, Noriko, Yokomizo, Takehiko, Sugimoto, Naotoshi, Sakurada, Soutaro, Shigematsu, Hiroshi, Takuwa, Yoh
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Cell Growth and Development
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC102182/
https://ncbi.nlm.nih.gov/pubmed/11094076
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