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The Matrix Protein of Vesicular Stomatitis Virus Inhibits Nucleocytoplasmic Transport When It Is in the Nucleus and Associated with Nuclear Pore Complexes

The matrix (M) protein of vesicular stomatitis virus (VSV) is a potent inhibitor of bidirectional nuclear transport. Here we demonstrate that inhibition occurs when M protein is in the nucleus of Xenopus laevis oocytes and that M activity is readily reversed by a monoclonal antibody (αM). We identif...

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Detalhes bibliográficos
Main Authors: Petersen, Jeannine M., Her, Lu-Shuin, Varvel, Virgil, Lund, Elsebet, Dahlberg, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102164/
https://ncbi.nlm.nih.gov/pubmed/11046154
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