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Acetylation by PCAF Enhances CIITA Nuclear Accumulation and Transactivation of Major Histocompatibility Complex Class II Genes

The class II transactivator (CIITA), the master regulator of the tissue-specific and interferon gamma-inducible expression of major histocompatibility complex class II genes, synergizes with the histone acetylase coactivator CBP to activate gene transcription. Here we demonstrate that in addition to...

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Udgivet i:Mol Cell Biol
Principais autores: Spilianakis, Charalambos, Papamatheakis, Joseph, Kretsovali, Androniki
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102155/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11046145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.22.8489-8498.2000
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