Putative Immunodominant Human Immunodeficiency Virus-Specific CD8(+) T-Cell Responses Cannot Be Predicted by Major Histocompatibility Complex Class I Haplotype

Recent studies of human immunodeficiency virus (HIV)-specific CD8(+) T cells have focused on responses to single, usually HLA-A2-restricted epitopes as surrogate measures of the overall response to HIV. However, the assumption that a response to one epitope is representative of the total response is...

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Bibliographic Details
Main Authors: Betts, Michael R., Casazza, Joseph P., Patterson, Brent A., Waldrop, Shar, Trigona, Wendy, Fu, Tong-Ming, Kern, Florian, Picker, Louis J., Koup, Richard A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC102113/
https://ncbi.nlm.nih.gov/pubmed/10982361
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