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Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion

REV1 functions in the DNA polymerase ζ mutagenesis pathway. To help understand the role of REV1 in lesion bypass, we have examined activities of purified human REV1 opposite various template bases and several different DNA lesions. Lacking a 3′→5′ proofreading exonuclease activity, purified human RE...

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Udgivet i:Nucleic Acids Res
Principais autores: Zhang, Yanbin, Wu, Xiaohua, Rechkoblit, Olga, Geacintov, Nicholas E., Taylor, John-Stephen, Wang, Zhigang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101843/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.7.1630
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