The zinc ion in the HNH motif of the endonuclease domain of colicin E7 is not required for DNA binding but is essential for DNA hydrolysis

The HNH motif was originally identified in the subfamily of HNH homing endonucleases, which initiate the process of the insertion of mobile genetic elements into specific sites. Several bacteria toxins, including colicin E7 (ColE7), also contain the 30 amino acid HNH motif in their nuclease domains....

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Ku, Wen-Yen, Liu, Yu-Wen, Hsu, Ya-Chein, Liao, Chen-Chung, Liang, Po-Huang, Yuan, Hanna S., Chak, Kin-Fu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2002
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.7.1670
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