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Transcutaneous Immunization with Bacterial ADP-Ribosylating Exotoxins, Subunits, and Unrelated Adjuvants

We have recently described a needle-free method of vaccination, transcutaneous immunization, consisting of the topical application of vaccine antigens to intact skin. While most proteins themselves are poor immunogens on the skin, we have shown that the addition of cholera toxin (CT), a mucosal adju...

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Autors principals: Scharton-Kersten, Tanya, Yu, Jian-mei, Vassell, Russell, O'Hagan, Derek, Alving, Carl R., Glenn, Gregory M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC101793/
https://ncbi.nlm.nih.gov/pubmed/10948159
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