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Application of Signature-Tagged Mutagenesis for Identification of Escherichia coli K1 Genes That Contribute to Invasion of Human Brain Microvascular Endothelial Cells

Escherichia coli K1 is the leading cause of gram-negative bacterial meningitis in neonates. It is principally due to our limited understanding of the pathogenesis of this disease that the morbidity and mortality rates remain unacceptably high. To identify genes required for E. coli K1 penetration of...

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Main Authors: Badger, Julie L., Wass, Carol A., Weissman, Scott J., Kim, Kwang Sik
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC101737/
https://ncbi.nlm.nih.gov/pubmed/10948125
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