The Major Acute-Phase Protein, Serum Amyloid P Component, in Mice Is Not Involved in Endogenous Resistance against Tumor Necrosis Factor Alpha-Induced Lethal Hepatitis, Shock, and Skin Necrosis

The proinflammatory cytokine tumor necrosis factor alpha (TNF-α) induces lethal hepatitis when injected into d-(+)-galactosamine-sensitized mice on the one hand or systemic inflammatory response syndrome (SIRS) in normal mice on the other hand. We studied whether serum amyloid P component (SAP), the...

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Pubblicato in:	Infect Immun
Autori principali:	Van Molle, Wim, Hochepied, Tino, Brouckaert, Peter, Libert, Claude
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Host Response and Inflammation
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101728/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10948120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.9.5026-5029.2000
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