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Recombination or heterogeneity: is there a second locus for adult polycystic kidney disease?

Twenty-four families with adult onset polycystic kidney disease were typed for markers flanking the PKD1 locus on chromosome 16. The aggregated results gave a significant lod score in favour of linkage to PKD1. Within this group of families two showed unusual features: recombinations, including doub...

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Detalles Bibliográficos
Main Authors: Elles, R G, Read, A P, Hodgkinson, K A, Watters, A, Harris, R
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1017176/
https://ncbi.nlm.nih.gov/pubmed/1975629
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