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Segregation analysis of dominant osteogenesis imperfecta in Italy.

We have performed linkage analysis in seven Italian families, in which mild osteogenesis imperfecta (OI) segregated as a dominant trait, by means of six DNA restriction fragment length polymorphisms (RFLPs) of type I collagen genes. OI type I was linked to the alpha 1(I) gene (COL1A1) in two familie...

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Veröffentlicht in:J Med Genet
Hauptverfasser: Mottes, M, Cugola, L, Cappello, N, Pignatti, P F
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 1990
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Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1017133/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1972760/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jmg.27.6.367
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