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Mutation and linkage disequilibrium analysis in genetic counselling of Spanish cystic fibrosis families.

We have analysed haplotypes for four DNA polymorphisms, closely linked to the cystic fibrosis (CF) gene, in 82 Spanish families, in which the CF probands are either homozygous for non-delta F508 mutations or heterozygous for the delta F508 deletion and other CF mutations. The analysis provides genet...

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Bibliografiska uppgifter
I publikationen:J Med Genet
Huvudupphovsmän: Casals, T, Nunes, V, Lázaro, C, Giménez, F J, Girbau, E, Volpini, V, Estivill, X
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMJ Publishing Group 1991
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1017113/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1770534/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jmg.28.11.771
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