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Linkage analysis in adenomatous polyposis coli: the use of four closely linked DNA probes in 20 UK families.

Linkage analysis was carried out on 20 unselected UK families segregating for adenomatous polyposis coli (APC) using four closely linked DNA probes. Significant lod scores were obtained between APC and three markers: pi 227 (D5S37) theta = 0.16; C11p11 (D5S71) theta = 0.10; and YN5.48 (D5S81) theta...

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Detalhes bibliográficos
Publicado no:J Med Genet
Main Authors: Cachon-Gonzalez, M B, Delhanty, J D, Burn, J, Tsioupra, K, Davis, M B, Attwood, J, Chapman, P
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1017054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1658324/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jmg.28.10.681
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