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Immunohistochemical studies show truncated dystrophins in the myotubes of three fetuses at risk for Duchenne muscular dystrophy.

We have performed immunohistochemical studies on muscle tissue of three 12 week old fetuses at risk for DMD, using antisera directed against regions located NH2-proximally and centrally in the rod shaped spectrin-like domain and against the COOH-terminus of dystrophin. All three fetuses had a family...

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Autors principals: Ginjaar, I B, Bakker, E, van Paassen, M M, den Dunnen, J T, Wessels, A, Zubrzycka-Gaarn, E E, Moorman, A F, van Ommen, G J
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1016976/
https://ncbi.nlm.nih.gov/pubmed/1920366
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