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A convenient multiplex PCR system for the detection of dystrophin gene deletions: a comparative analysis with cDNA hybridisation shows mistypings by both methods.

Existing reactions for the multiplex PCR amplification of exons in the dystrophin gene have been modified to produce two multiplex reactions which separately cover the 5' and 3' major deletion 'hotspots' in the gene, and together detect approximately 98% of all deletions detectab...

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Detalhes bibliográficos
Publicado no:J Med Genet
Main Authors: Abbs, S, Yau, S C, Clark, S, Mathew, C G, Bobrow, M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1016847/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1865467/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jmg.28.5.304
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