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Identification and HLA Restriction of Naturally Derived Th1-Cell Epitopes from the Secreted Mycobacterium tuberculosis Antigen 85B Recognized by Antigen-Specific Human CD4(+) T-Cell Lines

Antigen 85B (Ag85B/MPT59) is a major secreted protein from Mycobacterium tuberculosis which is a promising candidate antigen for inclusion in novel subunit vaccines against tuberculosis (TB). The present study was undertaken to map naturally derived T-cell epitopes from M. tuberculosis Ag85B in rela...

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Detalhes bibliográficos
Main Authors: Mustafa, Abu S., Shaban, Fatema A., Abal, Adnan T., Al-Attiyah, Raja, Wiker, Harald G., Lundin, Knut E. A., Oftung, Fredrik, Huygen, Kris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC101670/
https://ncbi.nlm.nih.gov/pubmed/10858206
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