Inactivation of Pasteurella (Mannheimia) haemolytica Leukotoxin Causes Partial Attenuation of Virulence in a Calf Challenge Model

The leukotoxin of Pasteurella (Mannheimia) haemolytica is believed to play a significant role in pathogenesis, causing cell lysis and apoptosis that lead to the lung pathology characteristic of bovine shipping fever. Using a system for Cre-lox recombination, a nonpolar mutation within the lktC trans...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Highlander, Sarah K., Fedorova, Natalie D., Dusek, David M., Panciera, Roger, Alvarez, Laura E., Rinehart, Carol
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2000
Fag:	Molecular and Cellular Pathogenesis
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10858203/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.7.3916-3922.2000
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