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A genetic study of type 2 neurofibromatosis in the United Kingdom. I. Prevalence, mutation rate, fitness, and confirmation of maternal transmission effect on severity.

A clinical and genetic study of type 2 neurofibromatosis (NF2) has been carried out in the United Kingdom. Virtually complete ascertainment of cases in the north-west of England was achieved and suggests a population incidence of 1 in 33,000 to 40,000. In the UK as a whole, 150 cases have been ident...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Evans, D G, Huson, S M, Donnai, D, Neary, W, Blair, V, Teare, D, Newton, V, Strachan, T, Ramsden, R, Harris, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1016198/
https://ncbi.nlm.nih.gov/pubmed/1479598
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