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Confirmation of an association between RFLPs at the transforming growth factor-alpha locus and non-syndromic cleft lip and palate.

Three RFLPs at the TGFA locus were studied in 60 unrelated British Caucasian subjects with non-syndromic cleft lip/palate and 60 controls. A highly significant association between the TaqI RFLP and the occurrence of clefting was found (chi 2 = 15.04, p = less than 0.001). No significant association...

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Detalhes bibliográficos
Publicado no:J Med Genet
Main Authors: Holder, S E, Vintiner, G M, Farren, B, Malcolm, S, Winter, R M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1015988/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1352354/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jmg.29.6.390
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