Systemic Neutralization of Interleukin-8 Markedly Reduces Neutrophilic Pleocytosis during Experimental Lipopolysaccharide-Induced Meningitis in Rabbits

Interleukin-8 (IL-8) is elevated in the cerebrospinal fluid (CSF) of patients with meningitis and is proposed to participate in subarachnoid-space pleocytosis. However, intracisternal injection of IL-8 into rabbits failed to induce indices typical of meningitis (leukocyte, tumor necrosis factor, or...

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Autors principals: Dumont, Rachel A., Car, Bruce D., Voitenok, Nikolai N., Junker, Ursula, Moser, Bernhard, Zak, Oto, O'Reilly, Terence
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Molecular and Cellular Pathogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC101534/
https://ncbi.nlm.nih.gov/pubmed/10992482
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