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Recombinant Bovine Interleukin-1β Amplifies the Effects of Partially Purified Pasteurella haemolytica Leukotoxin on Bovine Neutrophils in a β(2)-Integrin-Dependent Manner

The influx and death of polymorphonuclear leukocytes within the infected lung are hallmarks of bovine pasteurellosis. Recent reports have shown that the Pasteurella haemolytica leukotoxin (LKT) and other RTX toxins bind β(2)-integrins on target cells. In this study we demonstrate that exposure of bo...

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Main Authors: Leite, F., Brown, J. F., Sylte, M. J., Briggs, R. E., Czuprynski, C. J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC101509/
https://ncbi.nlm.nih.gov/pubmed/10992457
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