High-Affinity Interaction between Gram-Negative Flagellin and a Cell Surface Polypeptide Results in Human Monocyte Activation

Flagella from diverse gram-negative bacteria induce tumor necrosis factor alpha (TNF-α) and interleukin-1β (IL-1β) synthesis by human monocytes (F. Ciacci-Woolwine, P. F. McDermott, and S. B. Mizel, Infect. Immun. 67:5176–5185, 1999). In this study, we establish that purified flagellin (FliC or FljB...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	McDermott, Patrick F., Ciacci-Woolwine, Federica, Snipes, James A., Mizel, Steven B.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2000
Subjects:	Host Response and Inflammation
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101501/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10992449/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.10.5525-5529.2000
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