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Factors regulating Hb F synthesis in thalassemic diseases

BACKGROUND: The thalassemic syndromes originate from mutations of the globin genes that cause, besides the characteristic clinical picture, also an increased Hb F amount. It is not yet clear if there are more factors, besides the beta globin genotype, determining the Hb F production. We have tried t...

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Detalhes bibliográficos
Main Authors: Mastropietro, Fabrizio, Modiano, Guido, Cappabianca, Maria Pia, Foglietta, Enrica, D'Asero, Carmelo, Mezzabotta, Mauro, Ponzini, Donatella, Maffei, Laura, Amato, Antonio, Lerone, Maria, Grisanti, Paola, Di Biagio, Paola, Rinaldi, Silvana, Bianco, Ida
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC101377/
https://ncbi.nlm.nih.gov/pubmed/11943067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2326-2-2
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