Φ29 DNA polymerase residues Tyr59, His61 and Phe69 of the highly conserved ExoII motif are essential for interaction with the terminal protein

Phage Φ29 encodes a DNA-dependent DNA polymerase belonging to the eukaryotic-type (family B) subgroup of DNA polymerases that use a protein as the primer for initiation of DNA synthesis. In one of the most important motifs present in the 3′→5′ exonucleolytic domain of proofreading DNA polymerases, t...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Eisenbrandt, Ralf, Lázaro, José M., Salas, Margarita, de Vega, Miguel
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2002
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101362/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.6.1379
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