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Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA
Heat-induced formation of 8-oxoguanine was demonstrated in DNA solutions in 10(–3) M phosphate buffer, pH 6.8, by enzyme-linked immunosorbent assays using monoclonal antibodies against 8-oxoguanine. A radiation-chemical yield of 3.7 × 10(–2) µmol J(–1) for 8-oxoguanine production in DNA upon γ-irrad...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC101361/ https://ncbi.nlm.nih.gov/pubmed/11884633 |
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