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The solution structure of an oligonucleotide duplex containing a 2′-deoxyadenosine-3-(2-hydroxyethyl)- 2′-deoxyuridine base pair determined by NMR and molecular dynamics studies
Determination of the solution structure of the duplex d(GCAAGTC(HE)AAAACG)·d(CGTTTTAGACTTGC) containing a 3-(2-hydroxyethyl)-2′-deoxyuridine·deoxyadenine (HE·A) base pair is reported. The three-dimensional solution structure, determined starting from 512 models via restrained molecular mechanics usi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC101359/ https://ncbi.nlm.nih.gov/pubmed/11884635 |
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