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Use of phytohaemagglutinin stimulated lymphocytes to study effects of hypoxanthine-guanine phosphoribosyltransferase (HGPRT) deficiency on polynucleotide and protein synthesis in the Lesch-Nyhan syndrome.

The incorporation of [14C]thymidine and [14C]uridine into the nucleoprotein, and [14C]phenylalanine into the protein by phytohaemagglutinin (PHA) stimulated lymphocytes from a patient with the Lesch-Nyhan syndrome [hypoxanthine-guanine phosphoribosyl transferase (EC 2.4.2.8 HGPRT) deficiency] and co...

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Detalhes bibliográficos
Publicado no:J Med Genet
Principais autores: McKeran, R O, Watts, R W
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1013367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/933118/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jmg.13.2.91
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