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Beta-thalassaemia: increased chromosomal anomalies in lymphocyte cultures.

Lymphocyte cultures from homozygotes for the beta-thalassaemia gene were found to contain chromosomal gaps, breaks, and rearrangements more often than those from controls. Culture time seemed to have a determinant effect on the results. The possible influence of folic acid deficiency is discussed.

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Autori principali: Côté, G B, Papadakou-Lagoyanni, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1979
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1012781/
https://ncbi.nlm.nih.gov/pubmed/469887
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